Hepa-B for Pediatric Vaccine | 0.5ml | Price | ePharma
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Hepa-B For Pediatric Vaccine 0.5ml

Generic: Hepatitis B Vaccine (rDNA)

Type: Injection

Pack Size: 1 Pc

Hepatitis B Vaccine (rDNA) is used to prevent Hepatitis B infection. It helps develop immunity by initiating a mild, non-illness-causing infection, stimulating the body's immune system to produce protective antibodies.


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MRP: ৳ 450 4% Off

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✅ Description:

The Hepatitis B Vaccine is a non-infectious recombinant DNA vaccine. It is a sterile suspension consisting of purified surface antigens from the hepatitis B virus. This antigen is obtained by culturing genetically engineered yeast cells (Saccharomyces cerevisiae), which carry the gene coding for the HBsAg. The HBsAg protein, produced in yeast cells, is purified through multiple physicochemical processes and then formulated as a suspension with the antigen adsorbed on aluminum hydroxide. No human-derived substances are used in the manufacturing process.

Safety Advices


Alcohol
UNSAFE

It is not known whether it is safe to consume alcohol with Hepatitis B Vaccine. Please consult your doctor.


Pregnancy
CONSULT YOUR DOCTOR

Hepatitis B Vaccine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects on the developing baby; however, there are limited human studies.


Breastfeeding
CONSULT YOUR DOCTOR

Hepatitis B Vaccine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Driving
SAFE

Hepatitis B vaccine does not usually affect your ability to drive.


Kidney
SAFE IF PRESCRIBED

Hepatitis B Vaccine is safe to use in patients with kidney disease. No dose adjustment of the Hepatitis B Vaccine is recommended.
However, please inform your doctor if you have an underlying kidney disease.


Liver
SAFE IF PRESCRIBED

Hepatitis B Vaccine is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Hepatitis B Vaccine may not be needed in these patients. Please consult your doctor.

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✔️ Uses:

To prevent Hepatiis B virus For active immunization against the, Hepatitis B infection

✔️ Composition

Each 0.5 ml dose contains more than 10 mcg of hepatitis B surface antigen adsorbed on Aluminium Hydroxide gel, equivalent to 0.25 mg of Al3+.

Each 1 ml dose contains more than 20 mcg of hepatitis B surface antigen adsorbed on Aluminium Hydroxide gel, equivalent to 0.5 mg of Al3+.

✔️ Pharmacology

Hepatitis B vaccines are utilized for active immunization against hepatitis B infection. These vaccines work by introducing the hepatitis B surface antigen (HBsAg) into the body. The HBsAg is adsorbed onto aluminum hydroxide or a similar adsorbent. When administered, the vaccine stimulates the immune system to produce antibodies against the HBsAg, thereby providing immunity and protecting the individual from future hepatitis B infections.

✔️ Tolerability and Reactions

Hepatitis B vaccine is generally well tolerated. Most recipients experience some reactions upon vaccination, which are typically mild and short-lived. These reactions primarily include local reactions at the injection site, such as erythema (redness), induration (hardening), and tenderness. Systemic reactions, such as malaise (general discomfort), headache, diarrhea, vomiting, myalgia (muscle pain), and elevated temperature, are reported less commonly. In very rare cases, allergic-type reactions, such as pruritus (itching), rash, and urticaria (hives), may occur.

✔️ Dosage Guidelines

Neonates, Infants, and Children up to 19 Years of Age:

  • Recommended Dose: >10 mcg of antigen protein in 0.5 ml.

Adults 19 Years of Age and Older:

  • Recommended Dose: >20 mcg of antigen in 1 ml.
✔️ Primary Immunization Schedule for All Ages

Standard Schedule (3 doses):

  1. First Dose: On the elected date.
  2. Second Dose: 1 month after the first dose.
  3. Third Dose: 6 months after the first dose.
✔️ Accelerated Schedule (4 doses):
  1. First Dose: On the elected date.
  2. Second Dose: 1 month after the first dose.
  3. Third Dose: 2 months after the first dose.
  4. Fourth Dose: 12 months after the first dose.

This accelerated schedule provides quicker protection and is expected to enhance patient compliance.

✔️ Neonates Born to Hepatitis B Surface Antigen-Positive Mothers (4 doses of 10 micrograms):
  1. First Dose: At birth with Hepatitis B immunoglobulin injection (at a separate site).
  2. Second Dose: 1 month after the first dose.
  3. Third Dose: 2 months after the first dose.
  4. Fourth Dose: 12 months after the first dose.
✔️ Travelers Departing Within 1 Month (Adults over 18 Years):
  1. First Dose: On the elected date.
  2. Second Dose: 7 days after the first dose.
  3. Third Dose: 21 days after the first dose.
  4. Fourth Dose: 12 months after the first dose.
✔️ Renal Insufficiency (Including Hemodialysis Patients) - Adults and Children Over 16 Years (4 doses of 40 micrograms):
  1. First Dose: On the appropriate date.
  2. Second Dose: 1 month after the first dose.
  3. Third Dose: 2 months after the first dose.
  4. Fourth Dose: 6 months after the first dose.

The immunization schedule and booster doses may need to be adjusted for individuals with low antibody concentrations.

✔️ Booster Vaccinations

For individuals with a normal immune status who have been vaccinated, the necessity of booster doses of the Hepatitis B vaccine has not been established. However, booster doses are recommended for hemodialysis patients and other immunocompromised individuals.

✔️ Administration:

Method of Administration:

  • Route: Intramuscular injection only.
  • Do Not: Inject intravenously.
  • Injection Sites:
    • Adults and Children (over 1 year): Deltoid muscle.
    • Children (under 1 year): Anterolateral aspect of the thigh.

Preparation for Administration:

  1. Shake Well: Shake the vaccine well before use to obtain a homogenous, turbid white suspension. Avoid vigorous shaking.
  2. Visual Inspection: Inspect the vaccine visually for any particulate matter and discoloration before administration. Do not use the vaccine if these conditions are present.
  3. Usage: Use the vaccine as supplied without any dilution.

Co-Administration:

  • Simultaneous Administration: Hepatitis B vaccine can be administered concurrently with other vaccines, such as Diphtheria, Tetanus, Pertussis (DTP), Polio (OPV), Measles, Mumps and Rubella (MMR), Haemophilus influenzae b, Hepatitis A, and BCG vaccines. Administer these vaccines at separate sites using separate syringes.
  • Do Not Mix: Do not mix the Hepatitis B vaccine with other vaccines or medicinal products in the same syringe.
✔️ Interaction

Reduced response to vaccination when used concurrently with immunosuppressants such as corticosteroids or antineoplastics.

✔️ Contraindications

Hypersensitivity to any component of the vaccine, including yeast, is a contraindication. This vaccine is contraindicated in patients with previous hypersensitivity to any Hepatitis B virus-containing vaccine.

✔️ Pregnancy & Lactation

The effect of Hepatitis B on fetal development or reproduction capacity has not been evaluated. However, it should only be used during pregnancy when there is a high risk of infection. Adequate human data on use during lactation and adequate animal reproduction studies are not available. It may be administered to nursing mothers only if needed.

✔️ Precautions & Warnings

If any alcohol or disinfectant is used for cleansing the skin it should be allowed to evaporate before vaccination otherwise inactivation of live vaccines may occur. Lactation: not known if excreted in breast milk

✔️ Storage Conditions:

Keep out of the reach and sight of children. Store at +2°C to +8°C. Transportation should also be at +2°C to +8°C. Protect from light. Do not freeze.

Frequently Asked Questions (FAQ)

If you miss a dose, contact your healthcare provider to reschedule. It's important to complete the full vaccination series for optimal protection, but the series does not need to be restarted. Your provider will guide you on when to receive the remaining doses.

The Hepatitis B vaccine is available at healthcare providers' offices, clinics, and public health departments, online Platform epharma. It's also commonly available through vaccination programs in schools and workplaces.

The Hepatitis B vaccine specifically protects against the Hepatitis B virus. However, it also indirectly prevents Hepatitis D, which requires a Hepatitis B infection to occur. It does not protect against other types of hepatitis, such as Hepatitis A, C, or E.

The standard vaccination schedule typically involves three doses. The second dose is given one month after the first, and the third dose is administered six months after the first dose. A different schedule may be used in certain situations, such as for infants born to infected mothers or for post-exposure prophylaxis.

Yes, the Hepatitis B vaccine is safe for pregnant women and is often recommended if there is a high risk of Hepatitis B exposure during pregnancy.

The vaccine stimulates the body's immune system to produce antibodies against the Hepatitis B virus, thereby providing protection against the infection.

Yes, the Hepatitis B vaccine is safe and effective. It is widely used and recommended by health authorities worldwide. Side effects, if any, are usually mild and temporary, such as soreness at the injection site or mild fever.

Hepatitis B can be transmitted through: Contact with infected blood and body fluids via breaks in the skin (e.g., bites, cuts, sores) Sharing personal items that have blood or body fluids on them (e.g., toothbrushes, razors) Having unprotected sex with an infected person Sharing needles for drug injection Being stuck with a used needle Close household contact with an infected person

Immunization is recommended for people of all ages, particularly those at increased risk of exposure to the Hepatitis B virus. This includes: Babies born to infected mothers Individuals in close contact with infected blood or body fluids People sharing personal items like toothbrushes or razors with an infected person Those engaging in unprotected sex with an infected person People who share needles for drug injection Individuals accidentally stuck with a used needle Household contacts of Hepatitis B patients Residents and staff of institutions for the developmentally disabled Kidney dialysis patients Travelers to countries where Hepatitis B is common People with HIV, hemophilia, thalassemia, sickle cell anemia, or cirrhosis Military personnel at increased risk Morticians and embalmers Prisoners Users of illicit injectable drugs First responders like police and fire department personnel

The Hepatitis B vaccine is used for active immunization against infection caused by all known subtypes of the Hepatitis B virus. It can also help prevent Hepatitis D (caused by the delta virus) because Hepatitis D does not occur without a Hepatitis B infection.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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